The Full-Stack Healthcare
Communication API.
Securely connect your platform or solution to a national network of providers and systems through a single API.
Healthcare Has A Communication Problem, Not A Technology Problem.
A healthcare communication API is a software interface that enables platforms and solutions to exchange clinical content including referrals, records, messages, and documents across providers, EHRs, and standards through a single integration. Kno2 gives your platform send, receive, and find capabilities across every provider, format, and system. Building on Kno2 means inheriting a national network instead of building one connection at a time.
Stop building. Start connecting.
Integration Without the Patchwork
You should not have to spend months or even years building out point to point solutions for each provider and system you need to reach, navigating certification cycles, translating between standards, and maintaining every connection as specifications change and vendors update. That’s not building a product, it’s running a full interoperability department. With Kno2’s healthcare communication API, you connect just once to a network that handles the standards, certifications, vendor complexity, and ongoing maintenance behind the scenes, so you never have to.
Connect once, inherit the network.
A single API unlocks the full-stack network.
Stop maintaining interop infrastructure.
Eliminate the build and maintain burden.
Future-proof your platform.
Every new network, standard, or participant compounds your value.
When We Say “Full Stack,” We Mean It
For Kno2, full-stack communication isn’t just a tagline. It’s a structural commitment across four dimensions of how clinical information actually moves.
All Forms of Exchange
From fax to FHIR and everything in between. Kno2’s API natively supports HL7v2, FHIR resources, CDA documents, PDFs and more across APIs, Direct messaging, HIE profiles, and the legacy channels still moving the majority of clinical information today. Your platform connects once. The network handles the translation across every standard.
Every Care Setting
Most healthcare APIs cover the top health system and provider EHRs and call it done. Kno2 does that, but we also connect systems and providers across the continuum including independent practices, specialty clinics, behavioral health, post-acute, home health, and the rural and community providers that everyone else routes around.
All Systems
The healthcare technology landscape is fragmented across hundreds of EHRs and clinical platforms, and most of them don’t natively talk to each other. Kno2’s Communication API connects to all of them. Your customers don’t get asked which EHR they use before you can support them, because the answer is always yes.
All Workflows
Clinical communication doesn’t happen in one format or one workflow. It spans referrals, transitions of care, orders and results, prior authorizations, care summaries, clinical notes, and the images and attachments that travel with them. Kno2 carries all of it, structured and unstructured alike, so the workflow never has to bend to fit the technology.
Why Kno2?
Full-stack
By Design
Not a single standard. Not a single point solution.
Network
Density
TEFCA + aggregated networks. You connect to all public networks, HIEs and our private network.
Built for the Continuum
Every care setting, every provider, every workflow.
| Point-to-point interfaces | Kno2's Communication API | |
|---|---|---|
| Setup time | 6–12 months per connection | One integration, weeks not months |
| Standards support | Built and maintained by your team | Handled by Kno2 across every standard |
| Maintenance | Permanent engineering tax | Owned by Kno2 |
| Network reach | Limited to vendors you've built | Every provider in the national and Kno2 network |
| New EHRs | New build, new certification | Already connected |
| Cost model | Scales with every integration | One integration, one cost |
Built for the Teams Building Healthcare.
EHR Vendors
Integrate once, and inherit a national interoperability story your customers can use on day one. Replace the maintenance burden of building Direct, FHIR, IHE, and fax support in-house with a single API that handles every standard your customers expect.
Health Technology Companies
For health tech companies building on top of clinical workflows, Kno2 is the connective tissue. Plug into the network without becoming an interoperability company yourself.
Provider & Payer Organizations
For health systems with internal development teams, Kno2’s API extends what your platforms can already do. Build custom care coordination tools, support transitions across your network, and connect to community providers outside your walls.
…Supporting the Workflows They Use
Referrals & Transitions
Send and receive across care settings.
Patient Record Retrieval
Find and pull clinical data on demand.
Secure Clinical Messaging
Push critical patient messages and communications to any provider across the ecosystem.
See Kno2 in Action
Testimonials
What It Means To Be Kno2 Connected
From Integration to Exchange In Three Steps
1. Connect
Single integration to the Kno2 API.
2. Configure
Set network preferences, exchange agreements, routing.
3. Exchange
Send, receive, and find across the network.
Kno2 Blog
Why Your Interoperability Strategy Is Missing 80% of Care In the US, the vast
By Travis White, Sr Vice President of Solutions Strategy and Network Growth Information
In behavioral health and substance abuse centers across America, patient information is stuck. According
Get Kno2 Connected
Healthcare Communication API
FAQs
A healthcare communication API is a software interface that enables platforms to exchange clinical content like referrals, records, messages, and documents across providers, EHRs and clinical systems, and standards through a single integration. Instead of building separate connections to each EHR or system, network, or standard, platforms and solutions connect once to the API and inherit access to the entire network on the other side. Kno2’s healthcare communication API gives platforms SEND, RECEIVE, and FIND capabilities across every provider, format, and system in the network, replacing the dozens of point-to-point integrations a platform would otherwise need to maintain.
Integration with a healthcare network follows three steps when using Kno2’s API:
- Connect. Your team completes a single API integration to Kno2’s network, which handles authentication, trust, security, and connectivity to the network on your behalf.
- Configure. Set network preferences, define exchange agreements with your partners, and configure routing rules for the clinical content your platform sends and receives.
- Exchange. Your platform SENDS, RECEIVES, and FINDS clinical content across every provider in the Kno2 network, using the formats and workflows your customers already rely on.
A healthcare communication API needs to support the full range of standards still in active use across clinical communication, including HL7v2, FHIR, Direct, IHE profiles, CDA and PDF documents, and the legacy channels like fax that still move the majority of clinical information today. Supporting only the modern standards leaves significant portions of the care continuum unreachable, particularly in post-acute, behavioral health, and rural settings. Kno2’s Communication API supports every standard the network uses, so your platform connects once and reaches every provider, regardless of what infrastructure they run on.
A healthcare API replaces the dozens of point-to-point integrations a platform would otherwise need to exchange clinical content across the care continuum. Point-to-point integrations require separate vendor relationships, contracts, certifications, standards translation, and ongoing maintenance for every EHR, system, or network you connect to, creating a permanent engineering burden that grows with every new integration. A healthcare communication API consolidates all of that into a single integration, with the API provider owning the maintenance, trust, network terms, standards translation, and network expansion on your behalf. The result is faster time to market, lower engineering costs, and broader provider reach than point-to-point integrations can deliver.